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SRC Antibody (N-term)

SRC Antibody (N-term)

Item no.	ABC-AP7718a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IF, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	SRC, SRC1, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src
Available
Primary Accession	P12931
Antigen Type	Synthetic Peptide
Application	WB, IF, IHC-P
Bio Background	The gene for SRC is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC, the protein encoded by this gene, is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in SRC could be involved in the malignant progression of colon cancer.
Bio References	Lopez, R.G., et al., J. Biol. Chem. 278(42):41316-41325 (2003). Horn, S., et al., Oncogene 22(46):7170-7180 (2003). Hakam, A., et al., Dig. Dis. Sci. 48(10):1972-1978 (2003). Ito, H., et al., Surgery 134(2):221-226 (2003). Bouchard, M.J., et al., J. Virol. 77(14):7713-7719 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB3093
Gene ID	6714
Gene Name	SRC (HGNC:11283)
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Confocal immunofluorescent analysis of SRC Antibody (N-term)(Cat#AP7718a) with A375 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of lysates from MCF-7, rat PC-12, mouse C2C12 cell line (from left to right), using SRC Antibody (R14)(Cat. #AP7718a).AP7718a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 3	IHC-P
Dilution image 3	1:50~100
Isotype	Rabbit Ig
Calculated MW	59835
Antigen Region	1-30
Antigen Source	HUMAN
Target/Specificity	This SRC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SRC.
NCBI Accession	NP_005408.1; NP_938033.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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