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CASP9 Antibody (S196)

CASP9 Antibody (S196)

Item no.	ABC-AP7974a
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Caspase-9, CASP9, MCH6, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, Caspase-9 subunit p35, Caspase-9 subunit p10, APAF-3, ICE-LAP6, CASP-9
Available
Primary Accession	P55211
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	Caspase 9 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade.
Bio References	Martin, M.C., et al., J. Biol. Chem. 280(15):15449-15455 (2005). Raina, D., et al., J. Biol. Chem. 280(12):11147-11151 (2005). Cornelis, S., et al., Oncogene 24(9):1552-1562 (2005). Mohammad, R.M., et al., Mol. Cancer Ther. 4(1):13-21 (2005). Tacconi, S., et al., Exp. Neurol. 190(1):254-262 (2004).
Clonality	Polyclonal
Clone/Animal Names	RB6899
Gene ID	842
Gene Name	CASP9
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-CASP9 Antibody (S196) (Cat.#AP7974a) in Jurkat cell line lysates (35ug/lane). CASP9 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human hepatocarcinoma with CASP9 Antibody (S196), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Legend image 3	Flow cytometric analysis of MDA-231 cells using CASP9 Antibody (S196)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	46281
Antigen Source	HUMAN
Target/Specificity	This CASP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S196 of human CASP9.
NCBI Accession	NP_001220.2; NP_001264983.1; NP_127463.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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