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Fructose 6 Phosphate Kinase (PFKM) Antibody (C-term)

Fructose 6 Phosphate Kinase (PFKM) Antibody (C-term)

Item no.	ABC-AP8137b
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications	WB, IF, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PFKM, PFKX, Phosphofructo-1-kinase isozyme A, PFK-A, ATP-dependent 6-phosphofructokinase, PFK-M, ATP-PFK {ECO:0000255\|HAMAP-Rule:MF_03184}, 27111 {ECO:0000255\|HAMAP-Rule:MF_03184}, Phosphohexokinase {ECO:0000255\|HAMAP-Rule:MF_03184}, muscle type {ECO:0000255\|HAMAP-Rule:MF_03184}, 6-phosphofructokinase type A
Available
Primary Accession	P08237
Antigen Type	Synthetic Peptide
Application	IF, IHC-P, WB
Bio Background	Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1, 6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P). Only M type PFK isozyme is expressed in mature muscle, while erythrocytes contain both L and M subunits. Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7), also known as Tarui disease.
Bio References	Howard, T.D., et al., Genomics 34(1):122-127 (1996). Vasconcelos, O., et al., Proc. Natl. Acad. Sci. U.S.A. 92(22):10322-10326 (1995). Raben, N., et al., J. Biol. Chem. 268(7):4963-4967 (1993). Yamasaki, T., et al., Gene 104(2):277-282 (1991). Sharma, P.M., et al., J. Biol. Chem. 265(16):9006-9010 (1990).
Clonality	Polyclonal
Clone/Animal Names	RB3908
Gene ID	5213
Gene Name	PFKM
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Confocal immunofluorescent analysis of Fructose 6 Phosphate Kinase (PFKM) Antibody(C-term)(Cat#AP8137b) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of PFKM polyclonal antibody (Cat. #AP8137b) in Hela cell line lysate. PFKM(arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human skeletal muscle reacted with PFKM Antibody (C-term)(Cat.#AP8137b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Legend image 4	Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PFKM antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 4	IHC-P
Dilution image 4	1:50~100
Other Accession	Q60HD9
Predicted	Pr
Isotype	Rabbit Ig
Calculated MW	85183
Antigen Region	746-776
Antigen Source	HUMAN
Target/Specificity	This Fructose 6 Phosphate Kinase (PFKM) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 746-776 amino acids from the C-terminal region of human Fructose 6 Phosphate Kinase (PFKM).
NCBI Accession	NP_000280.1; NP_001160158.1; NP_001160159.1; NP_001160160.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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