IL1B Antibody (Center)

Primary Antibodies; Cancer; Cardiovascular; Immunology; Metabolism; Neuroscience; Signal Transduction; Inflammasome; Inflammatory response; Toll-Like receptor signaling; Cytokine; Cytokine, IL-1-like; Inflammation mediated by chemokine and cytokine signaling; Lysosome; Pyroptosis

IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system  CNS) is found to contribute to inflammatory pain hypersensitivity.

RB21917

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Pr, Rb

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide