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LY75 Antibody (Center)

LY75 Antibody (Center)

Item no.	ABC-AP8994c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	LY75, CD205, CLEC13B, DEC-205, C-type lectin domain family 13 member B, gp200-MR6, Ly-75, Lymphocyte antigen 75
Available
Primary Accession	O60449
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	LY75 acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. It causes reduced proliferation of B-lymphocytes.
Bio References	Kato, M., et.al., Immunogenetics 47 (6), 442-450 (1998) McKay, P.F., et.al., Eur. J. Immunol. 28 (12), 4071-4083 (1998)
Clonality	Polyclonal
Clone/Animal Names	RB23558
Gene ID	100526664; 4065
Gene Name	LY75
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of LY75 Antibody (Center) (Cat. #AP8994c) in HL-60 cell line lysates (35ug/lane). LY75 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human spleen tissue reacted with LY75 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	LY75 Antibody (Center) (Cat. #AP8994c) flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	198311
Antigen Region	646-675
Antigen Source	HUMAN
Target/Specificity	This LY75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 646-675 amino acids from the Central region of human LY75.
NCBI Accession	NP_001185688.1; NP_001185689.1; NP_002340.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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