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IL10 Antibody (Center)

IL10 Antibody (Center)

Item no.	ABC-AP9112C
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	IL-10, IL10, Interleukin-10, Cytokine synthesis inhibitory factor, CSIF
Available
Primary Accession	P22301
Antigen Type	Synthetic Peptide
Application	FC, WB, IHC-P
Bio Background	The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Bio References	Trajkov, D., et.al., Indian J Tuberc 56 (3), 117-131 (2009) Kim, J.M., et.al., J. Immunol. 148 (11), 3618-3623 (1992)
Clonality	Polyclonal
Clone/Animal Names	RB21234
Gene ID	3586
Gene Name	IL10
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of IL10 Antibody (Center) (Cat. #AP9112c) in MDA-MB435 cell line lysates (35ug/lane). IL10 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human breast carcinoma reacted with IL10 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Legend image 3	IL10 Antibody (Center) (Cat. #AP9112c) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	P79338; P03180
Predicted	EBV, Pr
Isotype	Rabbit Ig
Calculated MW	20517
Antigen Region	27-53
Antigen Source	HUMAN
Target/Specificity	This IL10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-53 amino acids from the Central region of human IL10.
NCBI Accession	NP_000563.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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