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Alexa Fluor™ 647-Labeled Human HLA-A*11:01&B2M&KRAS (VVGAGGVGK) Complex Protein (Monomer)

Alexa Fluor™ 647-Labeled Human HLA-A*11:01&B2M&KRAS (VVGAGGVGK) Complex Protein (Monomer)

Item no.	HLS-HA2H9-200ug
Manufacturer	ACROBiosystems
Amount	100 ug x 2
Quantity options	100 ug x 2 25 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Alexa Fluor 647, HIS
Purity	90%
Formula	PBS, pH7.4
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein / Fluorescent labeled protein
Manufacturer - Conjugate / Tag	C-10xHis, AF647 Labeled
Shipping Temperature	RT
Storage Conditions	-20°C, avoid light
Molecular Weight	36.4 kDa and 14.0 kDa
Manufacturer - Format	Powder
Description	Alexa Fluor 647-Labeled Human HLA-A11:01&B2M&KRAS (VVGAGGVGK) Complex Protein (HLS-HA2H9) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A11:01) & Ile 21 - Met 119 (B2M) & VVGAGGVGK peptide (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M) & VVGAGGVGK).
Background	The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Human HLA-A1101 KRAS (VVGAGGVGK) complex protein is a complex of HLA-A1101 of the MHC Class I, B2M, and VVGAGGVGK peptide of the KRAS.
Molecule	HLA-A*1101 \| B2M \| KRAS (VVGAGGVGK)
Exp Region	Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVGAGGVGK peptide
Characteristics	Alexa Fluor 647-Labeled Human HLA-A*11:01&B2M&KRAS (VVGAGGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRAS peptide.This protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 36.4 kDa and 14.0 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

HLS-HA2H9-200ug-datasheet.pdf

HLS-HA2H9-200ug-safety-datasheet.pdf