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YKL-05-099

YKL-05-099

Item no.	HY-101147-250mg
Manufacturer	MedChem Express
CASRN	1936529-65-5
Amount	250 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 250 mg 25 mg 50 mg 5 mg
Specific against	other
Purity	99.76
Smiles	O=C1N(C2=NC=C(OC)C=C2)C3=NC(NC4=CC=C(C5CCN(C)CC5)C=C4OC)=NC=C3CN1C6=C(C)C=CC=C6Cl
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Salt-inducible Kinase (SIK)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	600.11
Product Description	YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM)[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO : ≥ 75 mg/mL
Manufacturer - Pathway	Immunology/Inflammation
Clinical information	No Development Reported
Isoform	SIK1; SIK3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-101147-250mg-safety-datasheet.pdf