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Pemetrexed

Pemetrexed

Item no.	HY-10820-500mg
Manufacturer	MedChem Express
CASRN	137281-23-3
Amount	500 mg
Quantity options	100 mg 10 mM/1 mL 200 mg 500 mg 50 mg
Specific against	other
Purity	99.95
Smiles	O=C1NC(N)=NC2=C1C(CCC3=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3)=CN2
Alias	LY231514
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Antifolate; Autophagy
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	427.41
Product Description	Pemetrexed (LY231514) is an antifolate, the Ki values of the pentaglutamate of Pemetrexed (LY231514) are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 250 mg/mL (ultrasonic)\|H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Autophagy; Cell Cycle/DNA Damage
Clinical information	Launched

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