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Brequinar

Brequinar

Item no.	HY-108325-25mg
Manufacturer	MedChem Express
CASRN	96187-53-0
Amount	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Specific against	other
Purity	99.89
Smiles	O=C(C1=C(C)C(C2=CC=C(C3=CC=CC=C3F)C=C2)=NC4=CC=C(F)C=C14)O
Alias	DUP785,NSC 368390
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Dihydroorotate Dehydrogenase; DNA/RNA Synthesis; SARS-CoV; Virus Protease
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	375.37
Product Description	Brequinar (DUP785) is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 5.2 nM for human DHODH. Brequinar has potent activities against a broad spectrum of viruses. Brequinar also has an anti-SARS2 activity.
Manufacturer - Research Area	Cancer; Infection; Inflammation/Immunology
Solubility	DMSO : 25 mg/mL (ultrasonic)\|Ethanol : < 1 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Clinical information	Phase 2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-108325-25mg-safety-datasheet.pdf