KH064

Item no.	HY-11059-1mg
Manufacturer	MedChem Express
CASRN	393569-31-8
Amount	1 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 500 ug 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.47
Citations	[1]Karl A Hansford, et al. D-Tyrosine as a chiral precusor to potent inhibitors of human nonpancreatic secretory phospholipase A2 (IIa) with antiinflammatory activity. Chembiochem. 2003 Mar 3;4(2-3):181-5.
Smiles	OC(CC[C@@H](CC1=CC=C(OCC2=CC=CC=C2)C=C1)NC(CCCCCCC3=CC=CC=C3)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Phospholipase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	487.63
Product Description	KH064, a D-tyrosine derivative, is an orally active, potent secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 29 nM for human nonpancreatic secretory PLA2 isoform IIa (hnpsPLA2-IIa). KH064 has anti-inflammatory activity[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Isoform	Phospholipase A
Clinical information	No Development Reported

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HY-11059-1mg-safety-datasheet.pdf