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Carbacyclin

Carbacyclin

Item no.	HY-112322-100ug
Manufacturer	MedChem Express
CASRN	69552-46-1
Amount	100 ug (2.85 mM x 100 uL in Methyl acetate)
Quantity options	100 ug (2.85 mM x 100 uL in Methyl acetate) 1 mg 500 ug (2.85 mM x 500 uL in Methyl acetate)
Category	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Type	Inhibitors
Specific against	other
Purity	99.0
Citations	[1]Takasuka M, et al. FTIR spectral study of intramolecular hydrogen bonding in thromboxane A2 receptor agonist (U-46619), prostaglandin (PG)E2, PGD2, PGF2 alpha, prostacyclin receptor agonist (carbacyclin), and their related compounds in dilute CCl4 solution: structure-activity relationships. J Med Chem. 1994 Jan 7;37(1):47-56.\|[2]Whittle BJ, et al. Carbacyclin--a potent stable prostacyclin analogue for the inhibition of platelet aggregation. Prostaglandins. 1980 Apr;19(4):605-27.\|[3]Kuroda T, et al. Carbacyclin induces carnitine palmitoyltransferase-1 in cardiomyocytes via peroxisome proliferator-activated receptor (PPAR) delta independent of the IP receptor signaling pathway. J Mol Cell Cardiol. 2007 Jul;43(1):54-62.
Smiles	O=C(O)CCC/C=C1C[C@@]2([H])C[C@@H](O)[C@H](/C=C/[C@@H](O)CCCCC)[C@@]2([H])C\1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Carbaprostacyclin,Carba-PGI2
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	PPAR; Prostaglandin Receptor
Shipping Temperature	Blue Ice
Storage Conditions	Solution, -20°C, 2 years
Molecular Weight	350.49
Product Description	Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation.
Manufacturer - Research Area	Cardiovascular Disease; Endocrinology
Solubility	DMSO : 5 mg/mL (ultrasonic; warming)
Manufacturer - Pathway	Cell Cycle/DNA Damage; GPCR/G Protein; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Isoform	IP
Clinical information	No Development Reported

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HY-112322-100ug-safety-datasheet.pdf