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AZ-Dyrk1B-33

AZ-Dyrk1B-33

Item no.	HY-117391-25mg
Manufacturer	MedChem Express
CASRN	1679330-37-0
Amount	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 250 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.95
Citations	[1]Kettle JG, et al. Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis. J Med Chem. 2015 Mar 26;58(6):2834-44.
Smiles	CC1=NC=CC(C2=CN(CC3=CC=CC=C3)C4=C2C=CN=C4)=N1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	DYRK
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	300.36
Product Description	AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor, with an IC50 of 7 nM[1].
Manufacturer - Research Area	Cancer; Metabolic Disease
Solubility	DMSO: 125 mg/mL (ultrasonic)
Manufacturer - Pathway	Protein Tyrosine Kinase/RTK
Isoform	DYRK1
Clinical information	No Development Reported

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HY-117391-25mg-safety-datasheet.pdf