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ML 315 (hydrochloride)

ML 315 (hydrochloride)

Item no.	HY-117608A-25mg
Manufacturer	MedChem Express
CASRN	2172559-91-8
Amount	25 mg
Quantity options	10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Standards, Ladders & Markers
Type	Standard
Specific against	other
Purity	98.75
Citations	[1]Coombs TC, et al. Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3654-61.
Smiles	[H]Cl.ClC1=CC(CNC2=NC=NC=C2C3=CC=C4OCOC4=C3)=CC(Cl)=C1
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	CDK; DYRK
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Product Description	ML 315 is a selective dual inhibitor of CDK and DYRK with IC50s of 68 nM and 282 nM, respectively. ML 315 is used in cancer and neurological disease research[1].
Manufacturer - Research Area	Cancer; Neurological Disease
Solubility	DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK
Clinical information	No Development Reported

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HY-117608A-25mg-safety-datasheet.pdf