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Propargyl-PEG2-NHBoc

Propargyl-PEG2-NHBoc

Item no.	HY-118808-1g
Manufacturer	MedChem Express
CASRN	869310-84-9
Amount	1 g
Quantity options	100 mg 1 ea 1 g 250 mg 50 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	97.0
Citations	[1]Nello Mainolfi, et al. rak degraders and uses thereof. US20190192668A1.
Smiles	O=C(NCCOCCOCC#C)OC(C)(C)C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	ADC Linker; PROTAC Linkers
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	243.30
Product Description	Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-NHBoc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related; PROTAC
Isoform	Alkyl/ether Linkers; Cleavable Linker; PEG Linkers
Clinical information	No Development Reported

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HY-118808-1g-safety-datasheet.pdf