Comparison

Elesclomol European Partner

Item no. HY-12040-200mg
Manufacturer MedChem Express
CASRN 488832-69-5
Amount 200 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 200 mg 500 mg 50 mg 5 mg
Specific against other
Purity 99.43
Smiles S=C(C1=CC=CC=C1)N(NC(CC(NN(C(C2=CC=CC=C2)=S)C)=O)=O)C
Alias STA-4783
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
Apoptosis; Cuproptosis; Reactive Oxygen Species (ROS)
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
400.5177
Product Description
Elesclomol (STA-4783) is a potent copper ionophore and promotes copper-dependent cell death (cuproptosis). Elesclomol specifically binds ferredoxin 1 (FDX1) α2/α3 helices and β5 strand. Elesclomol inhibits FDX1-mediated Fe-S cluster biosynthesis. Elesclomol is an oxidative stress inducer that induces cancer cell apoptosis. Elesclomol is a reactive oxygen species (ROS) inducer. Elesclomol can be used for Menkes and associated disorders of hereditary copper deficiency research[1][2][3][4].
Manufacturer - Research Area
Cancer
Solubility
DMSO : 100 mg/mL (ultrasonic)
Manufacturer - Pathway
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Clinical information
Phase 3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 mg
Available: In stock
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