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NS-1619

NS-1619

Item no.	HY-12496-25mg
Manufacturer	MedChem Express
CASRN	153587-01-0
Amount	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Specific against	other
Purity	99.32
Smiles	O=C1NC2=CC(C(F)(F)F)=CC=C2N1C3=CC(C(F)(F)F)=CC=C3O
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Apoptosis; Potassium Channel
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	362.23
Product Description	NS-1619 is an opener of large conductance Ca2+-activated K+ (BK) channel. NS-1619 is a highly effective relaxant with an EC50 of about 10-30 μM in several smooth muscles of blood vessels and other tissues[1]. NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells[2].
Manufacturer - Research Area	Cancer; Cardiovascular Disease
Solubility	DMSO : ≥ 31 mg/mL
Manufacturer - Pathway	Apoptosis; Membrane Transporter/Ion Channel
Clinical information	No Development Reported

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HY-12496-25mg-safety-datasheet.pdf