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Thalidomide-NH-C6-NH2 (hydrochloride)

Thalidomide-NH-C6-NH2 (hydrochloride)

Item no.	HY-129704B-25mg
Manufacturer	MedChem Express
CASRN	2375194-37-7
Amount	25 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.62
Citations	[1]Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. [2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
Smiles	[H]Cl.O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCN)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	408.88
Product Description	Thalidomide-NH-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 125 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; Autophagy; PROTAC
Isoform	Cereblon
Clinical information	No Development Reported

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HY-129704B-25mg-safety-datasheet.pdf