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A 410099.1, amine-Boc (hydrochloride)

A 410099.1, amine-Boc (hydrochloride)

Item no.	HY-136269-5mg
Manufacturer	MedChem Express
CASRN	2374122-37-7
Amount	5 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.71
Citations	[1]Christopher P Tinworth, et al. PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding. ACS Chem Biol.2019 Mar 15;14(3):342-347
Smiles	O=C(N(C[C@H]1N)[C@@H](C1)C(N[C@H]2C3=CC=CC=C3CCC2)=O)[C@H](C4CCCCC4)NC([C@H](C)N(C)C(OC(C)(C)C)=O)=O.Cl
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	E3 Ligase Ligand-Linker Conjugates
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, protect from light)
Molecular Weight	620.22
Product Description	A 410099.1, amine-Boc hydrochloride is a functionalized IAP ligand and can be used for the synthesis of PROTACs, such as PROTACs targeting BTK (PROTACs 4 and 5)[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	PROTAC
Isoform	cIAP1
Clinical information	No Development Reported

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HY-136269-5mg-safety-datasheet.pdf