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Fatostatin

Fatostatin

Item no.	HY-14452-200mg
Manufacturer	MedChem Express
CASRN	125256-00-0
Amount	200 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 200 mg 25 mg 50 mg 5 mg
Specific against	other
Purity	99.85
Smiles	CCCC1=NC=CC(C2=NC(C3=CC=C(C)C=C3)=CS2)=C1
Alias	125B11
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Fatty Acid Synthase (FASN)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	294.41
Product Description	Fatostatin (125B11), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin decreases the transcription of lipogenic genes in cells. Fatostatin possesses antitumor properties, and lowers hyperglycemia in ob/ob mice[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 27 mg/mL
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

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