MQA-P

Item no.	HY-149203-5mg
Manufacturer	MedChem Express
Amount	5 mg
Quantity options	10 mM/1 mL 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Citations	[1]Li Fan, et al. Multifunctional Fluorescent Probe for Simultaneous Detection of ONOO-, Viscosity, and Polarity and Its Application in Ferroptosis and Cancer Models. Anal Chem. 2023 Apr 4;95(13):5780-5787.
Smiles	CN(C1=CC=C(C=C1)/C=C/C=C/C2=CC=[N+](C3=C2C=CC=C3)CC4=CC=C(C=C4)OP(C5=CC=CC=C5)(C6=CC=CC=C6)=O)C.[Br-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Dye Reagents
Manufacturer - Targets	Fluorescent Dye
Shipping Temperature	Room temperature
Molecular Weight	687.60
Product Description	MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO-, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO- (λem=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λem>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N, N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images[1].
Manufacturer - Research Area	Others
Solubility	10 mM in DMSO
Manufacturer - Pathway	Others
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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