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FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2

Item no.	HY-150408-5mg
Manufacturer	MedChem Express
CASRN	2241669-84-9
Amount	5 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.85
Citations	[1]Takahashi D, et al. AUTACs: Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76(5):797-810.e10.
Smiles	NCCCOCCOCCOCCCNC([C@H](CSC1=NC2=C(N=C(N)NC2=O)N1CC3=CC=C(F)C=C3)NC(C)=O)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	AUTACs
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	622.71
Product Description	FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4 (HY-134640). AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Autophagy; PROTAC
Clinical information	No Development Reported

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HY-150408-5mg-safety-datasheet.pdf