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SMO-IN-2

SMO-IN-2

Item no.	HY-150564-10mg
Manufacturer	MedChem Express
CASRN	1822355-27-0
Amount	10 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.12
Citations	[1]Ji D, et al. Design, synthesis and biological evaluation of anthranilamide derivatives as potent SMO inhibitors. Bioorg Med Chem. 2020 Mar 15;28(6):115354.
Smiles	O=C(N(C)C1CCN(C(C2=CC=CC=C2NC3=CC=NN3C)=O)CC1)C4=CC=C(F)C=C4C(F)(F)F
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Hedgehog; Smo
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	503.49
Product Description	SMO-IN-2 is a potent smoothened (SMO) inhibitor with an IC50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 10 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Stem Cell/Wnt
Clinical information	No Development Reported

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HY-150564-10mg-safety-datasheet.pdf