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UNC0638

UNC0638

Item no.	HY-15273-25mg
Manufacturer	MedChem Express
CASRN	1255580-76-7
Amount	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Specific against	other
Purity	99.48
Smiles	CC(N1CCC(NC2=C3C=C(OC)C(OCCCN4CCCC4)=CC3=NC(C5CCCCC5)=N2)CC1)C
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Autophagy; Histone Methyltransferase; Influenza Virus; VSV
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	509.73
Product Description	UNC0638, a chemical probe, selectively inhibits G9a and GLP histone methyltransferases with IC50 of 15 nM and 19 nM, respectively. UNC0638 inhibits TNBC cell invasion and migration in vitro. UNC0638 is also an inhibitor of EHMT1/2 and induces fetal hemoglobin (HbF) expression in human erythroid progenitor cell culture. In addition, UNC0638 has anti-FMDV (foot-and-mouth disease virus) and anti-VSV (vesicular stomatitis virus) activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets[1][2][3][4][5].
Manufacturer - Research Area	Cancer; Infection
Solubility	1M HCl : 100 mg/mL (ultrasonic; adjust pH to 1 with HCl)\|DMSO : 33.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Autophagy; Epigenetics
Clinical information	No Development Reported
Isoform	EHMT1/GLP/KMT1D; EHMT2/G9a/KMT1C

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-15273-25mg-safety-datasheet.pdf