« Back
Home /
Ribociclib

Ribociclib

Item no.	HY-15777-250mg
Manufacturer	MedChem Express
CASRN	1211441-98-3
Amount	250 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 g 250 mg 500 mg 50 mg 5 mg
Specific against	other
Purity	99.94
Smiles	O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5
Alias	LEE011
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	CDK
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	434.54
Product Description	RRibociclib (LEE011) is an ATP-competitive and orally active CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1, 000-fold less potent against the cyclin B/CDK1 complex[1][1].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 6.25 mg/mL (ultrasonic)
Manufacturer - Pathway	Cell Cycle/DNA Damage
Clinical information	Launched
Isoform	CDK4; CDK6

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-15777-250mg-safety-datasheet.pdf