M3554

Item no.	HY-158109
Manufacturer	MedChem Express
Amount	1 ea
Quantity options	1 ea 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	99.39
Dry ice	Yes
Citations	[1]Amendt C, et al. Abstract ND08: M3554, a novel anti-GD2 antibody drug conjugate[J]. Cancer Research, 2024, 84(7_Supplement): ND08-ND08.
Smiles	[M3554]
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Dry ice
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Antibody-Drug Conjugates (ADCs); CD2
Shipping Temperature	Dry Ice
Storage Conditions	-80°C, protect from light
Product Description	M3554 is a novel anti-GD2 ADC designed based on humanized ch14.18 anti-GD2 antibody and has anti-tumor activity. The cytotoxicity of M3554 against the GD2-positive neuroblastoma cell line CHP134 was in the subnanomolar IC50 range.
Manufacturer - Research Area	cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Clinical information	Phase 1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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