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ISD (sodium)

ISD (sodium)

Item no.	HY-160225-1mg
Manufacturer	MedChem Express
Amount	1 mg
Quantity options	1 ea 10 mg 1 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Nucleic acids
Specific against	other
Purity	98.02
Citations	[1]Stetson DB, Medzhitov R. Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity. 2006;24(1):93-103.
Smiles	[ISD (sodium)]
ECLASS 10.1	32160414
ECLASS 11.0	32160414
UNSPSC	41105324
Shipping Condition	Cool pack
Available
Manufacturer - Type	Oligonucleotides
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	STING
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture)
Product Description	ISD (interferon stimulatory DNA) sodium is a non-CpG oligomer from the Listeria monocytogenes genome. When transfected into cells, ISD sodium strongly enhances the expression of IFN-β. This ISD-induced response is mediated by the STING-TBK1-IRF3 signaling axis[1].
Manufacturer - Research Area	Inflammation/Immunology
Solubility	10 mM in DMSO\|10 mM in H2O
Manufacturer - Pathway	Immunology/Inflammation
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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