« Back
Home /
Zonisamide (Standard)

Zonisamide (Standard)

Item no.	HY-B0124R
Manufacturer	MedChem Express
CASRN	68291-97-4
Amount	1 ea
Quantity options	1 ea 100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Other Chemicals
Type	Standard
Specific against	other
Purity	0.9
Citations	[1]Kawajiri S, et al. Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD. Neurosci Lett. 2010 Sep 6;481(2):88-91. \|[2]Ueda Y, et al. Effect of zonisamide on molecular regulation of glutamate and GABA transporter proteins during epileptogenesis in rats with hippocampal seizures. Brain Res Mol Brain Res. 2003 Aug 19;116(1-2):1-6. \|[3]Wu Q, et al. Zonisamide alleviates cardiac hypertrophy in rats by increasing Hrd1 expression and inhibiting endoplasmic reticulum stress. Acta Pharmacol Sin. 2021 Oct;42(10):1587-1597.\|[4]De Simone G, et al. Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. Bioorg Med Chem Lett. 2005 May 2;15(9):2315-20.
Smiles	O=S(CC1=NOC2=C1C=CC=C2)(N)=O
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Alias	AD 810 (Standard),CI 912 (Standard)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference Standards
Manufacturer - Targets	Apoptosis; Carbonic Anhydrase; Reference Standards
Shipping Temperature	Room temperature
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	212.23
Product Description	Zonisamide (Standard) is the analytical standard of Zonisamide. This product is intended for research and analytical applications. Zonisamide (AD 810) is an orally active carbonic anhydrase inhibitor, with Kis of 35.2 and 20.6 nM for hCA II and hCA V, respectively. Zonisamide exerts neuroprotective effects through anti-apoptosis and upregulating MnSOD levels. Zonisamide also increases the expression of Hrd1, thereby improving cardiac function in AAC rats. Zonisamide can be used in studies of seizure, parkinson’s disease and cardiac hypertrophy[1][2][3][4].
Manufacturer - Research Area	Neurological Disease
Manufacturer - Pathway	Apoptosis; Metabolic Enzyme/Protease; Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 ea

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question