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Acetylcholine (chloride)

Acetylcholine (chloride)

Item no.	HY-B0282-25g
Manufacturer	MedChem Express
CASRN	60-31-1
Amount	25 g
Quantity options	10 g 10 mM/1 mL 1 g 25 g 500 mg 5 g
Category	Neuroscience Neural Signaling Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.91
Citations	[1]Prashant Tiwari, et al. Basic and modern concepts on cholinergic receptor: A review. Asian Pac J Trop Dis. 2013 Oct;3(5): 413-420.\|[2]A Young, et al. Diarrhoea of famine and malnutrition--investigations using a rat model. 2--Ileal hypersecretion induced by starvation. Gut. 1990 Feb;31(2):162-9.\|[3]Xia Lei, et al. Effects of acetylcholine chloride on intracellular calcium concentration of cultured sweat gland epithelial cells. Arch Dermatol Res. 2008 Aug;300(7):335-41.\|[4]P F Zabrodskii, et al. Effect of acetylcholine on mortality of mice from sepsis and proinflammatory cytokine production. Bull Exp Biol Med. 2011 Jan;150(3):340-2.\|[5]Zhaolin Chen, et al. Inhibition of p53 Mutant Peptide Aggregation In Vitro by Cationic Osmolyte Acetylcholine Chloride. Protein Pept Lett. 2017;24(4):353-357. Biochim Biophys Acta Mol Basis Dis. 2024 Aug 30:167488.\|Biomed Pharmacother. 2024 Jul 12:177:117105.\|bioRxiv. 2023 Oct 13.\|BMC Pulm Med. 2021 Jun 5;21(1):189.\|Cells. 2024 Oct 14;13(20):1697.\|Front Cardiovasc Med. 2021 Jun 16;8:679240.\|J Ethnopharmacol. 2024 Aug 22:118707.\|J Hazard Mater. 2023 Dec 14, 133248.\|J Hazard Mater. 2024 Sep 5:479:135690.\|Mol Cell Endocrinol. 2025 Jan 21:599:112464.\|Mol Metab. 2023 Sep 26, 101811.\|Proc Natl Acad Sci U S A. 2024 June 26.\|Redox Biol. 2023 Dec 18:69:103004.\|Trends Biotechnol. 2025 Jan 7:S0167-7799(24)00355-X.\|Int J Mol Sci. 2023 Apr 16, 24(8), 7356.\|Nat Commun. 2023 Sep 21;14(1):5891.
Smiles	O=C(OCC[N+](C)(C)C)C.[Cl-]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	ACh (chloride)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Calcium Channel; Endogenous Metabolite; nAChR
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	181.66
Product Description	Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5].
Manufacturer - Research Area	Neurological Disease; Cancer
Solubility	DMSO: 62.5 mg/mL (ultrasonic)\|H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Isoform	Human Endogenous Metabolite
Clinical information	Launched

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HY-B0282-25g-safety-datasheet.pdf