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Diphenhydramine (Standard)

Diphenhydramine (Standard)

Item no.	HY-B0303R
Manufacturer	MedChem Express
CASRN	58-73-1
Amount	1 ea
Quantity options	1 ea 100 mg 10 mg 25 mg 50 mg
Category	Reagents & Chemicals Other Chemicals
Type	Standard
Specific against	other
Purity	98.69
Citations	[1]Jason P Berninger, et al. Effects of the antihistamine diphenhydramine on selected aquatic organisms. Environ Toxicol Chem. 2011 Sep;30(9):2065-72.\|[2]Föhr KJ, et al. Open channel block of NMDA receptors by diphenhydramine. Neuropharmacology. 2015 Dec;99:459-70. \|[3]Ehling S, et al. Diphenhydramine pharmacokinetics after oral and intravenous administration of diphenhydramine and oral administration of dimenhydrinate to healthy dogs, and pharmacodynamic effect on histamine-induced wheal formation: a pilot study. Vet Dermatol. 2019 Apr;30(2):91-e24. \|[4]Hamano H, et al. Diphenhydramine may be a preventive medicine against cisplatin-induced kidney toxicity. Kidney Int. 2021 Apr;99(4):885-899.
Smiles	CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference Standards
Manufacturer - Targets	Bacterial; Endogenous Metabolite; Histamine Receptor; iGluR; Reference Standards
Shipping Temperature	Room temperature
Storage Conditions	4°C, sealed storage, away from light and moisture
Molecular Weight	255.35
Product Description	Diphenhydramine (Standard) is the analytical standard of Diphenhydramine. This product is intended for research and analytical applications. Diphenhydramine is a first-generation histamine H1-receptor antagonist with anti-cholinergic effect. Diphenhydramine hydrochloride can across the ovine blood-brain barrier (BBB) [1][2][3].
Manufacturer - Research Area	Cancer; Inflammation/Immunology; Neurological Disease
Manufacturer - Pathway	Anti-infection; GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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