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Cyclosporin A

Cyclosporin A

Item no.	HY-B0579-5g
Manufacturer	MedChem Express
CASRN	59865-13-3
Amount	5 g
Quantity options	100 mg 10 mM/1 mL 1 g 200 mg 500 mg 5 g
Specific against	other
Purity	99.94
Smiles	C/C=C/C[C@H]([C@@H](O)[C@@]1(N(C)C([C@]([H])(C(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@]([H])(CC(C)C)N(C)C([C@@H](C)NC([C@H](C)NC([C@@H](N(C([C@@]([H])(NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)=O)=O)=O)=O)=O)[H])C
Alias	Cyclosporine A,Ciclosporin A,CsA
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Complement System; Cyclophilin; Molecular Glues
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, protect from light)
Molecular Weight	1202.61
Product Description	Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM[3]. Cyclosporin A also inhibits CD11a/CD18 adhesion[8].
Manufacturer - Research Area	Inflammation/Immunology; Cancer
Solubility	DMSO : 62.5 mg/mL (ultrasonic)\|Ethanol : 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Immunology/Inflammation; PROTAC
Clinical information	Launched
Isoform	Cyclophilin D

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HY-B0579-5g-safety-datasheet.pdf