Comparison

Rabeprazole (sodium) European Partner

Item no. HY-B0656A-25mg
Manufacturer MedChem Express
CASRN 117976-90-6
Amount 25 mg
Quantity options 100 mg 10mM/1mL 10 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.67
Citations Front Immunol. 2022 Jun 21;13:895869.
Nat Commun. 2023 Jul 14;14(1):4217.
Results Chem. 2024 Oct.
[1]Tara A Shea, et al. Identification of Proton-Pump Inhibitor Drugs That Inhibit <i>Trichomonas Vaginalis</i> Uridine Nucleoside Ribohydrolase. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1080-4.
[2]Aly A M Shaalan, et al. Supplement With Calcium or Alendronate Suppresses Osteopenia Due to Long Term Rabeprazole Treatment in Female Mice: Influence on Bone TRAP and Osteopontin Levels. Front Pharmacol. 2020 May 13;11:583.
[3]Mengli Gu, et al. Rabeprazole Exhibits Antiproliferative Effects on Human Gastric Cancer Cell Lines. Oncol Lett. 2014 Oct;8(4):1739-1744.
Smiles O=S(C1=NC2=CC=CC=C2N1[Na])CC3=NC=CC(OCCCOC)=C3C
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias LY307640 (sodium)
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
COVID-19-immunoregulation
Manufacturer - Targets
Apoptosis; Bacterial; Proton Pump
Shipping Temperature
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Molecular Weight
381.42
Product Description
Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].
Manufacturer - Research Area
Inflammation/Immunology; Cancer
Solubility
DMSO : 100 mg/mL (ultrasonic)|H2O : 66.67 mg/mL (ultrasonic; adjust pH to 11 with 1M NaOH)
Manufacturer - Pathway
Anti-infection; Apoptosis; Membrane Transporter/Ion Channel
Clinical information
Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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