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alpha-Mangostin (Standard)

alpha-Mangostin (Standard)

Item no.	HY-N0328R-50mg
Manufacturer	MedChem Express
CASRN	01.11.6147
Amount	50 mg
Quantity options	1 ea 100 mg 10 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Other Chemicals
Type	Standard
Specific against	other
Purity	99.44
Citations	[1]Kim HJ, et al. Discovery of α-mangostin as a novel competitive inhibitor against mutant isocitrate dehydrogenase-1. Bioorg Med Chem Lett. 2015 Dec 1;25(23):5625-31.\|[2]Lee HN, et al. Antitumor and apoptosis-inducing effects of α-mangostin extracted from the pericarp of the mangosteen fruit (Garcinia mangostana L.) in YD-15 tongue mucoepidermoid carcinoma cells. Int J Mol Med. 2016 Apr;37(4):939-48.
Smiles	O=C1C2=C(OC3=C1C(C/C=C(C)\C)=C(OC)C(O)=C3)C=C(O)C(C/C=C(C)\C)=C2O
ECLASS 10.1	42021590
ECLASS 11.0	42021590
UNSPSC	12352202
Alias	α-Mangostin (Standard)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference Standards
Manufacturer - Targets	Apoptosis; Bacterial; Fungal; Reactive Oxygen Species (ROS); Reference Standards; Virus Protease
Shipping Temperature	Room Temperature
Storage Conditions	4°C, sealed storage, away from light and moisture
Molecular Weight	410.46
Product Description	alpha-Mangostin (Standard) is the analytical standard of alpha-Mangostin. This product is intended for research and analytical applications. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM.
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Clinical information	Phase 2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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