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Vasicine

Vasicine

Item no.	HY-N1103-1mg
Manufacturer	MedChem Express
CASRN	6159-55-3
Amount	1 mg
Quantity options	10 mg 1 ea 1 mg 25 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.0
Citations	[1]Grange JM, et al. Activity of bromhexine and ambroxol, semi-synthetic derivatives of vasicine from the Indian shrub Adhatoda vasica, against Mycobacterium tuberculosis in vitro. J Ethnopharmacol. 1996 Jan;50(1):49-53.\|[2]Jiang T, et al., Protective Effect Of Vasicine Against Myocardial Infarction In Rats Via Modulation Of Oxidative Stress, Inflammation, And The PI3K/Akt Pathway. Drug Des Devel Ther. 2019 Oct 31;13:3773-3784.\|[3]Singh VK, et al., Anti-secretory and cyto-protective effects of peganine hydrochloride isolated from the seeds of Peganum harmala on gastric ulcers. Phytomedicine. 2013 Oct 15;20(13):1180-5.
Smiles	O[C@H]1CCN2C1=NC3=C(C=CC=C3)C2
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Peganine
Shipping Condition	Cool pack
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Akt; Bacterial; PI3K
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	188.23
Product Description	Vasicine (peganine) is a quinazoline alkaloid isolated from Justicia adhatoda. Vasicine activates PI3K/Akt signaling pathway, exhibits antioxidant, anti-inflammatory and antibacterial activities[1][2][3].
Manufacturer - Research Area	Infection; Inflammation/Immunology
Solubility	DMSO: 83.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; PI3K/Akt/mTOR
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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