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Citric acid

Citric acid

Item no.	HY-N1428-2g
Manufacturer	MedChem Express
CASRN	77-92-9
Amount	2 g
Quantity options	100 mg 10 mM/1 mL 1 g 200 mg 2 g 500 g 500 mg 5 g
Category	Food Safety Neuroscience Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Neural Development Inhibitors & Compound Libraries Small Molecules Acid Determination
Type	Inhibitors
Specific against	other
Purity	99.93
Citations	[1]Chen X, et al. Study on injury effect of food additive citric acid on liver tissue in mice. Cytotechnology. 2014 Mar;66(2):275-82.\|[2]Chen X, Lv Q, Liu Y, Deng W. Effects of the food additive, citric acid, on kidney cells of mice. Biotech Histochem. 2015 Jan;90(1):38-44. \|[3]Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct;33(10):4411-20.\|[4]Ciriminna R, et al. Citric acid: emerging applications of key biotechnology industrial product. Chem Cent J. 2017 Mar 8;11:22. Food Chem. 2023 Mar 30;405(Pt A):134807. Food Chem. 2025 May 31:489:144992. J Sep Sci. 2025 Nov;48(11):e70312. Mol Cancer. 2025 Oct 2;24(1):238. Nature. 2025 Jul;643(8070):192-200. New J Chem. 03 Aug 2022. Adv Sci (Weinh). 2025 May 21:e2505359. Adv Sci (Weinh). 2025 Nov 6:e07384. Adv Sci (Weinh). 2025 Nov 7:e18323. Bioengineered. 2021 Dec;12(2):11610-11621. Biol Trace Elem Res. 2024 Feb;202(2):701-712. Biol Trace Elem Res. 2025 Jun 13. Biomed Pharmacother. 2023 Oct:166:115333. bioRxiv. 2025 Jul 24:2025.07.24.666650. Drug Des Devel Ther. 2024 Feb 1:18:259-275. Front Immunol. 2024 Oct 1:15:1397727. Front Mol Biosci. 2022 Jul 22:9:952608. Int J Biol Sci. 2024 Aug 6;20(11):4222-4237. J Biochem Mol Toxicol. 2025 Oct;39(10):e70484. mBio. 2025 Mar 24:e0012725. Oxid Med Cell Longev. 2022 Apr 25;2022:3846217. Phytomedicine. 2025 Apr 5:141:156702. Res Sq. 2025 Aug 08. Research Square Preprint. 2021 Jul. Bone. 2025 Jan 28:193:117411. Regen Biomater. 2024 Aug 22:11:rbae098. Insect Biochem Mol Biol. 2023 Jun:157:103958. J Exp Clin Cancer Res. 2025 Jul 8;44(1):195. J Virol. 2023 Jul 27;97(7):e0051223. Mol Ther. 2025 Nov 7:S1525-0016(25)00870-6.
Smiles	OC(CC(CC(O)=O)(C(O)=O)O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Category	Reference compound / Active compounds; API; Natural Products
Manufacturer - Targets	Apoptosis; Bacterial; Endogenous Metabolite
Manufacturer - HS Code	H319, H335
Shipping Temperature	Room Temperature
Storage Conditions	Store at room temperature 3 years
Molecular Weight	192.12
Product Description	Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries[1][2][3][4].
Manufacturer - Research Area	Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Clinical information	Launched
UNSPSC Code	12352211
Precautionary	H319, H335

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