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Lucicebtide

Lucicebtide

Item no.	HY-P10376-10mg
Manufacturer	MedChem Express
CASRN	2407100-74-5
Amount	10 mg
Quantity options	1 ea 10 mg 1 mg 5 mg
Category	Peptides & Proteins Peptides
Type	Peptides
Specific against	other
Purity	98.28
Citations	[1]Darvishi E, et al., Anticancer Activity of ST101, A Novel Antagonist of CCAAT/Enhancer Binding Protein β. Mol Cancer Ther. 2022 Nov 3;21(11):1632-1644.
Smiles	N=C(N)NCCC[C@H](C(O)=O)NC([C@@H](CCC(N)=O)NC([C@@H](CC(C)C)NC([C@@H](CCCCN)NC([C@@H](CC(C)C)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@@H](CC3=CC=CC=C3)NC([C@@H](CCC(N)=O)NC([C@@H](CC(N)=O)NC([C@@H](CCCNC(N)=N)NC([C@@H](CCCNC(N)=N)NC([C@@H](CCSC)NC([C@@H](CCCCN)NC([C@@H](CC4=CNC5=C4C=CC=C5)NC([C@@H](CCCCN)NC([C@@H](CCCCN)NC([C@@H](CC(C)C)NC([C@@H](CCC(O)=O)NC(CNC([C@@H](CCCNC(N)=N)NC([C@@H](C)NC([C@@H](CCC(N)=O)NC(CNC([C@@H](CC(C)C)NC([C@@H](CCCNC(N)=N)NC([C@@H](C)NC([C@@H](CCC(O)=O)NC([C@@H](CC(C)C)NC([C@@H](CCCNC(N)=N)NC([C@@H](CCC(O)=O)NC([C@@H](CC(C)C)NC([C@@H](CCC(O)=O)NC([C@@H](CCC(O)=O)NC([C@@H](CCCNC(N)=N)NC([C@@H](C)NC([C@@H](CCC(O)=O)NC([C@@H](C)NC([C@@H](C(C)C)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping condition	Cool pack
Available
Product Description	Lucicebtide (Compound ST101) is a selective antagonist for CCAAT/enhancer binding protein β (C/EBPβ). Lucicebtide binds to the leucine zipper domain of C/EBPβ, prevents its dimerization, and ubiquitin-dependently degrades C/EBPβ. Lucicebtide arrests cell cycle at G0/G1 phase. Lucicebtide exhibits cytotoxicity in cancer cells. Lucicebtide exhibits good pharmacokinetic characters and inhibits tumor growth in mouse model[1].
StorageTemperature	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Shipping	Blue Ice
Manufacturers Applications	Cancer-programmed cell death
MolecularWeight	4724.46
Clinical Information	No Development Reported
Manufacturers Research Area	Cancer
Solubility	DMSO : 0.99 mg/mL (ultrasonic; adjust pH to 5 with 1 M HCL)
Target	Others
Manufacturers Target	Others
Manufacturers Pathway	Others
Manufacturers Product type	Peptides

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HY-P10376-10mg-safety-datasheet.pdf