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Cortistatin 14 (mouse, rat)

Cortistatin 14 (mouse, rat)

Item no.	HY-P1212-5mg
Manufacturer	MedChem Express
CASRN	193829-96-8
Amount	5 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Peptides
Specific against	other
Purity	99.96
Citations	[1]Jiang J, et al. Centrally Administered Cortistation-14 Induces Antidepressant-Like Effects in Mice via MediatingGhrelin and GABAA Receptor Signaling Pathway. Front Pharmacol. 2018 Jul 19;9:767.\|[2]de Lecea L, et al. A cortical neuropeptide with neuronal depressant and sleep-modulating properties. Nature. 1996 May 16;381(6579):242-5.
Smiles	[H]N1CCC[C@H]1C(N[C@H]2CSSC[C@@H](C(N[C@H](C(O)=O)CCCCN)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](O)C)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC2=O)CCCCN)=O)CC(N)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)CC5=CNC6=C5C=CC=C6)=O)CCCCN)=O)=O)CC7=CC=CC=C7)=O)CO)=O)CO)=O)=O
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CST-14 (mouse,rat)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Peptides
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Somatostatin Receptor
Shipping Temperature	Blue Ice
Storage Conditions	-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Molecular Weight	1721.01
Product Description	Cortistatin 14, mouse, rat (CST-14, human, rat), a neuropeptide with neuronal depressant and sleep modulating properties, can bind to all five cloned somatostatin receptors (SSTRs) and ghrelin receptor to exert its biological activities and co-exists with GABA within the cortex and hippocampus[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Clinical information	No Development Reported

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HY-P1212-5mg-safety-datasheet.pdf