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Noggin, Mouse (CHO)

Noggin, Mouse (CHO)

Item no.	HY-P7086-100ug
Manufacturer	MedChem Express
Amount	100 ug
Quantity options	100 ug 10 ug 20 ug 2 ug 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Purity	97.00
Sequence	LRAAPAGGQH YLHIRPAPSD NLPLVDLIEH PDPIFDPKEK DLNETLLRSL LGGHYDPGFM ATSPPEDRPG GGGGPAGGAE DLAELDQLLR QRPSGAMPSE IKGLEFSEGL AQGKKQRLSK KLRRKLQMWL WSQTFCPVLY AWNDLGSRFW PRYVKVGSCF SKRSCSVPEG MVCKPSKSVH LTVLRWRCQR RGGQRCGWIP IQYPIISECK CSC
Citations	[1]Valenzuela DM, et al. Identification of mammalian noggin and its expression in the adult nervous system. J Neurosci. 1995 Sep;15(9):6077-84.\|[2]Brunet LJ, et al. Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton. Science. 1998 May 29;280(5368):1455-7.\|[3]Smith WC, et al. Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm. Nature. 1993 Feb 11;361(6412):547-9.\|[4]Groppe J, et al. Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. Nature. 2002 Dec 12;420(6916):636-42.\|[5]Rifas L. The role of noggin in human mesenchymal stem cell differentiation. J Cell Biochem. 2007 Mar 1;100(4):824-34.\|[6]Matsuura I, et al., BMP inhibition enhances axonal growth and functional recovery after spinal cord injury. J Neurochem. 2008 May;105(4):1471-9
Smiles	LRAAPAGGQH YLHIRPAPSD NLPLVDLIEH PDPIFDPKEK DLNETLLRSL LGGHYDPGFM ATSPPEDRPG GGGGPAGGAE DLAELDQLLR QRPSGAMPSE IKGLEFSEGL AQGKKQRLSK KLRRKLQMWL WSQTFCPVLY AWNDLGSRFW PRYVKVGSCF SKRSCSVPEG MVCKPSKSVH LTVLRWRCQR RGGQRCGWIP IQYPIISECK CSC
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Noggin Protein,Mouse (CHO),Mouse,CHO
Shipping Condition	Cool pack
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Blue Ice
Storage Conditions	Stored at -20°C for 2 years
Molecular Weight	Approximately 28-31 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Product Description	Noggin protein is an important BMP inhibitor that plays an indispensable role in the neural tube, somite growth, cartilage morphogenesis, and joint formation. Its homodimeric structure promotes significant interactions with GDF5 and possibly GDF6, inhibiting chondrocyte differentiation. Noggin Protein, Mouse (CHO) is the recombinant mouse-derived Noggin protein, expressed in CHO.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-P7086-100ug-safety-datasheet.pdf