Item no. |
ILG-C82F5-25ug |
Manufacturer |
ACROBiosystems
|
Amount |
25 ug |
Quantity options |
200 ug
25 ug
|
Format |
Solid |
Specific against |
Monkey (Cynomolgus, Simian) |
Host |
HEK293 |
Conjugate/Tag |
Biotin, Avi, Fc |
Purity |
90% |
Shipping condition |
Room temperature |
Available |
|
Manufacturer - Category |
Protein |
Manufacturer - Conjugate / Tag |
C-Fc & C-Avi | C-Fc & C-Avi, Biotin-labeled |
Shipping Temperature |
RT |
Storage Conditions |
-20°C |
Molecular Weight |
53.0 kDa & 77.4 kDa |
Description |
Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG Protein, Fc, Avitag&Fc, Avitag (ILG-C82F5) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Thr 240 & Glu 22 - Glu 213 & Leu 23 - Pro 255 (Accession # Q38J85-1 & H6WS54 & A0A2K5VGJ6). |
Background |
Both Interleukin-2 receptor subunit beta, Interleukin-2 receptor subunit alpha and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. |
Molecule |
IL-2 R beta & IL-2 R alpha & IL-2 R gamma |
Exp Region |
Ala 27 - Thr 240 & Glu 22 - Glu 213 & Leu 23 - Pro 255 |
Characteristics |
Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG Protein, Fc, Avitag&Fc, Avitag is produced by co-expression of IL-2RB and IL-2RA and IL-2RG, has a calculated MW of 53.0 kDa & 77.4 kDa. Subunit IL-2RB is fused with a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™) and subunit IL-2RA&IL-2RG is fused with a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein migrates as 64-70 kDa and 100-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
1.0 EU per μg |
Buffer |
PBS, pH7.4 |
Stability |
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Protectant |
trehalose |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.