Comparison

PF-04802367

Item no. DCC-DC21484-100mg
Manufacturer DCChemicals
CASRN 1962178-27-3
Amount 100 mg
Quantity options 100 mg 1 g 250 mg
Category
Type Inhibitors
Applications IC
Specific against other
Purity >98%
Smiles ClC1=C(C=CC(=C1)C1=C(C(NCCCN2C=NC=N2)=O)N=CO1)OC
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Manufacturer - Applications
PF04802367 is a potent, highly selective GSK-3 inhibitor with IC50 of 2.1 nM for human GSK-3β in enzyme assays; shows equal effectivity against GSK-3α and GSK-3β with IC50 of 10.0 and 9.0 nM respectively in mobility shift assays, inhibits phosphorylation of tau with an IC50 of 466 nM in a stable inducible CHO cell line over-expressing GSK-3β and substrate tau; modulates tau phosphorylation in vitro and in vivo.
Molecular Weight
361.782941818237

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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