« Back
Home /
Mezigdomide(CC-92480)

Mezigdomide(CC-92480)

Item no.	DCC-DC39084-250mg
Manufacturer	DCChemicals
CASRN	2259648-80-9
Amount	250 mg
Quantity options	100 mg 1 g 250 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Applications	ELISA, other
Specific against	other
Smiles	FC1C([H])=C(C#N)C([H])=C([H])C=1N1C([H])([H])C([H])([H])N(C([H])([H])C2C([H])=C([H])C(=C([H])C=2[H])C([H])([H])OC2=C([H])C([H])=C([H])C3C(N(C([H])([H])C=32)[C@]2([H])C(N([H])C(C([H])([H])C2([H])[H])=O)=O)=O)C([H])([H])C1([H])[H]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Manufacturer - Applications	Mezigdomide is a cereblon E3 ubiquitin ligase modulating agent with potential immunomodulating and antineoplastic activities. Mezigdomide specifically binds to cereblon (CRBN), thereby affecting the ubiquitin E3 ligase activity, and targeting certain substrate proteins for ubiquitination. This induces proteasome-mediated degradation of certain transcription factors, some of which are transcriptional repressors in T cells. This leads to modulation of the immune system, including activation of T lymphocytes, and downregulation of the activity of other proteins, some of which play key roles in the proliferation of certain cancer cell types.
Molecular Weight	567, 6101

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 250 mg

available

Delivery expected until 6/26/2025

Express Delivery: Save 3 days

Compare

Add to wishlist

Recommend by mail