Comparison

SR-0813

Item no. DCC-DC47894-100mg
Manufacturer DCChemicals
CASRN 2597186-19-9
Amount 100 mg
Quantity options 100 mg 1 g 250 mg
Category
Type Inhibitors
Applications IC
Specific against other
Purity >98%
Smiles S(NC1C=CC=C(C=1)C1=CN2C(C=CC(=C2)C(NC2CCC2)=O)=N1)(NCCN1CCCCC1)(=O)=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Manufacturer - Applications
SR-0813 is a potent and selective ENL/AF9 YEATS domain inhibitor. SR-0813 has IC50 and EC50 values of 25 nM and 205 nM for ENL YEATS domain, respectively. SR-0813 has IC50 and EC50 values of 311 nM and 76 nM (CETSA) for AF9 YEATS domain, respectively. SR-0813 binds MAP3K19 with over 100-fold lower affinity (Kd=3.5 μM) than ENL YEATS (Kd=30 nM). SR-0813 can be used for the research of acute leukemia.
Molecular Weight
496.624983787537

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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