Comparison

Arimoclomol European Partner

Item no. HY-106443-10mg
Manufacturer MedChem Express
CASRN 289893-25-0
Amount 10 mg
Quantity options 100 mg 10 mg 1 ea 5 mg
Category
Type Molecules
Specific against other
Purity 99.74
Citations [1]Rakonczay Z Jr, et al. Nontoxic heat shock protein coinducer BRX-220 protects against acute pancreatitis in rats. Free Radic Biol Med. 2002 Jun 15;32(12):1283-92.|[2]Phukan J. Arimoclomol, a coinducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis. IDrugs. 2010 Jul;13(7):482-96.
Smiles Cl/C(C1=C[N+]([O-])=CC=C1)=N\OC[C@H](O)CN2CCCCC2
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias BRX-220 (free base)
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Metabolism-protein/nucleotide metabolism
Manufacturer - Targets
HSP
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
313.78
Product Description
Arimoclomol (BRX-220 free base) is an orally active co-inducer of heat shock proteins (HSP)[1]. Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system[2].Arimoclomol can be used for the study of Niemann–Pick disease type C.
Manufacturer - Research Area
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Solubility
DMSO: 25 mg/mL (ultrasonic)
Manufacturer - Pathway
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Isoform
HSP
Clinical information
Launched

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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