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Hyaluronidase, Bovine testes

Hyaluronidase, Bovine testes

Item no.	HY-107910-25mg
Manufacturer	MedChem Express
CASRN	37326-33-3
Amount	25 mg
Quantity options	100 mg 10 mMx1 mL 10 mg 25 mg 500 mg 50 mg 5 mg
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Type	Inhibitors
Specific against	other
Citations	[1]Vartanian AJ, et al. Injected hyaluronidase reduces restylane-mediated cutaneous augmentation. Arch Facial Plast Surg. 2005 Jul-Aug;7(4):231-7.\|[2]Brandon E, et al. The Use of Hyaluronidase in Cosmetic Dermatology: A Review of the Literature. J Clin Investigat Dermatol. 2015;3(2): 7.\|[3]Apaza Ticona L, et al. Rubus urticifolius Compounds with Antioxidant Activity, and Inhibition Potential against Tyrosinase, Melanin, Hyaluronidase, Elastase, and Collagenase[J]. Pharmaceuticals (Basel). 2024 Jul 13;17(7):937.\|[4]Jung H. Hyaluronidase: An overview of its properties, applications, and side effects[J]. Arch Plast Surg. 2020 Jul;47(4):297-300.\|[5]Lee W, et al. Comparative Effectiveness of Different Interventions of Perivascular Hyaluronidase[J]. Plast Reconstr Surg. 2020 Apr;145(4):957-964.\|[6]Wang M, et al. Comparison of Intra-arterial and Subcutaneous Testicular Hyaluronidase Injection Treatments and the Vascular Complications of Hyaluronic Acid Filler[J]. Dermatol Surg. 2017 Feb;43(2):246-254.\|[7] Kim DW, et al. Vascular complications of hyaluronic acid fillers and the role of hyaluronidase in management. J Plast Reconstr Aesthet Surg. 2011 Dec;64(12):1590-5. \|[8]Gong H, et al. Hyaluronidase To Enhance Nanoparticle-Based Photodynamic Tumor Therapy. Nano Lett. 2016 Apr 13;16(4):2512-21. Cell Biosci. 2023 Aug 10;13(1):147.\|Cell Oncol (Dordr). 2024 Dec 24.\|Drug Dev Ind Pharm. 2023 Mar 27;1-37.\|Mol Cancer. 2024 Jan 10;23(1):12.\|Nat Commun. 2023 May 26;14(1):3050.\|Theranostics. 2023; 13(6):2040-2056.\|Cell Death Dis. 2025 Mar 20;16(1):190.
Smiles	[Hyaluronidase, Bovine testes]
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Hyaluronate 4-glycanohydrolase,Bovine testes,Hyaluronoglucosaminidase,Bovine testes
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	NF-κB
Shipping Temperature	Room Temperature
Storage Conditions	Store at 4°C for 2 years, protect from light
Molecular Weight	55000 (average)
Product Description	Hyaluronidase, Bovine testes (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is an endoglycosidase that depolymerizes Hyaluronic acid (HA) (HY-B0633A) by cleavage of glycosidic bonds. Hyaluronidase degrades HA and activates membrane receptors that trigger pathways converging in NF-κB activation. Hyaluronidase is employed in the research of granulomatous foreign body reactions, soft-tissue necrosis caused by vascular compromise and uncomplicated nodules, overcorrection, inflamed nodules or tissue ischemia associated with HA filler injection[1][2][3][4][5][6].
Manufacturer - Research Area	Inflammation/Immunology; Cancer
Solubility	H2O: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	NF-κB
Clinical information	Launched

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HY-107910-25mg-safety-datasheet.pdf