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Azoxymethane

Azoxymethane

Item no.	HY-111375-25mg
Manufacturer	MedChem Express
CASRN	25843-45-2
Amount	25 mg (135 mM x 2.5 mL in Water)
Quantity options	100 mg (135 mM x 10 mL in Water) 10 mMx1 mL 10 mg (135 mM x 1 mL in Water) 25 mg (135 mM x 2.5 mL in Water) 50 mg (135 mM x 5 mL in Water) 5 mg (135 mM x 500 uL in Water)
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Colorectal Cancer
Type	Inhibitors
Specific against	other
Purity	99.0
Citations	[1]Megaraj V, et al. Role of hepatic and intestinal p450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in mice. Chem Res Toxicol. 2014 Apr 21;27(4):656-62.\|[2]Whetstone RD, et al. Colon carcinogenesis in wild type and immune compromised mice after treatment with azoxymethane, and azoxymethane with dextran sodium sulfate. Mol Carcinog. 2016 Jul;55(7):1187-95.\|[3]Fichera A, et al. Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis. Cancer Res. 2007 Jan 15;67(2):827-35.
Smiles	C/[N+]([O-])=N/C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	AOM
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	DNA Alkylator/Crosslinker
Shipping Temperature	Blue Ice
Storage Conditions	Solution, -20°C, 2 years
Molecular Weight	74.08
Product Description	Azoxymethane is a colon carcinogen which leads to the formation of DNA adducts.
Manufacturer - Research Area	Cancer
Solubility	H2O: ≥ 200 mg/mL
Manufacturer - Pathway	Cell Cycle/DNA Damage
Clinical information	No Development Reported

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HY-111375-25mg-safety-datasheet.pdf