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N-Butanoyl-L-homoserine lactone

N-Butanoyl-L-homoserine lactone

Item no.	HY-114816-5g
Manufacturer	MedChem Express
CASRN	67605-85-0
Amount	5 g
Quantity options	100 mg 1 g 250 mg 50 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	98.0
Citations	[1]Keith Alan Charlton, et al. Methods for the Treatment of an Infectious Bacterial Disease with an Anti-Lactone or Lactone Derived Signal Molecules Antibody. US20130045208A1 [2]Zhao M, et al. C4-HSL aptamers for blocking qurom sensing and inhibiting biofilm formation in Pseudomonas aeruginosa and its structure prediction and analysis. PLoS One. 2019 Feb 19;14(2):e0212041. [3]Feng Sun, et al. Advance of the diversity of bacterial quorum sensing and quorum quenching. National Natural Science Foundation of China. Published online 9 October 2018.
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	C4-HSL, N-Butyryl-L-homoserine lactone
Shipping condition	Room temperature
Available
Manufacturer - Type	ADC Related
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	ADC Linker; Bacterial
Shipping Temperature	Room Temperature
Molecular Weight	171.196
Product Description	N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3].
Manufacturer - Research Area	Infection; Inflammation/Immunology
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Antibody-drug Conjugate/ADC Related; Anti-infection
Isoform	Cleavable Linker
Clinical information	No Development Reported

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HY-114816-5g-safety-datasheet.pdf