Comparison

HSP27 inhibitor J2 European Partner

Item no. HY-124653-100mg
Manufacturer MedChem Express
CASRN 2133499-85-9
Amount 100 mg
Quantity options 100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category
Type Inhibitors
Specific against other
Purity 99.70
Smiles O=C1C=C(C)OC2=C1C(O)=CC(OCC3SC3)=C2
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias J2
Shipping condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
HSP
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
264.30
Product Description
HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition [1] [2] .
Manufacturer - Research Area
Cancer
Solubility
DMSO : 20 mg/mL (ultrasonic)
Manufacturer - Pathway
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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