« Back
Home /
Hh-Ag1.5

Hh-Ag1.5

Item no.	HY-124899-1mg
Manufacturer	MedChem Express
CASRN	612542-14-0
Amount	1 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Purity	99.90
Citations	[1]Randall W King. Roughing Up Smoothened: Chemical Modulators of Hedgehog Signaling. J Biol. 2002 Nov 6;1(2):8. [2]Abhisek Mitra, et al. A Small Molecule Hedgehog Agonist HhAg1.5 Mediated Reprogramming Breaks the Quiescence of Noninjured Liver Stem Cells for Rescuing Liver Failure. Transl Res. 2019 Mar;205:44-50. [3]Maria Frank-Kamenetsky, et al. Small-molecule Modulators of Hedgehog Signaling: Identification and Characterization of Smoothened Agonists and Antagonists. J Biol. 2002 Nov 6;1(2):10. [4]Cynthia M Rominger, et al. Evidence for Allosteric Interactions of Antagonist Binding to the Smoothened Receptor. J Pharmacol Exp Ther. 2009 Jun;329(3):995-1005.
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	SAg1.5
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Hedgehog
Shipping Temperature	Room Temperature
Molecular Weight	526.04
Product Description	Hh-Ag1.5 (SAg1.5) is a potent Hedgehog (Hh) agonist with an EC50 of 1 nM[1]. Hh-Ag1.5 mediated reprogramming breaks the quiescence of noninjured liver stem cells for rescuing liver failure[2].
Manufacturer - Research Area	Metabolic Disease
Solubility	DMSO : 50 mg/mL (ultrasonic)
Manufacturer - Pathway	Stem Cell/Wnt
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-124899-1mg-safety-datasheet.pdf