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R(+)-Methylindazone

R(+)-Methylindazone

Item no.	HY-12693-25mg
Manufacturer	MedChem Express
CASRN	54197-31-8
Amount	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.17
Citations	[1]Landry DW, et al. Epithelial chloride channel. Development of inhibitory ligands. J Gen Physiol. 1987 Dec;90(6):779-98.\|[2]Landry DW, et al. Purification and reconstitution of chloride channels from kidney and trachea. Science. 1989 Jun 23;244(4911):1469-72.\|[3]Xiaoqin Fan, et al. A homogeneous time-resolved fluorescence-based high-throughput screening for discovery of inhibitors of Nef-sdAb19 interaction. Int J Oncol. 2015 Oct;47(4):1485-93.
Smiles	O=C(O)COC1=CC2=C(C([C@@](C)(C3CCCC3)C2)=O)C(Cl)=C1Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	R(+)-IAA-94
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Targets	Chloride Channel
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	357.23
Product Description	R(+)-Methylindazone (R(+)-IAA-94) is a potent indanyloxyacetic acid blocker of epithelial chloride channels. R(+)-Methylindazone inhibits Nef-sdAb19 (single-domain antibody) interaction and binds to negative factor (Nef)[1][2][3].
Manufacturer - Research Area	Others
Solubility	DMSO: 100 mg/mL (ultrasonic)\|H2O: < 0.1 mg/mL (ultrasonic)
Manufacturer - Pathway	Membrane Transporter/Ion Channel
Clinical information	No Development Reported

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HY-12693-25mg-safety-datasheet.pdf