Comparison

Azido-PEG4-C2-acid European Partner

Item no. HY-130653-5g
Manufacturer MedChem Express
CASRN 1257063-35-6
Amount 5 g
Quantity options 100 mg 1 g 250 mg 500 mg 50 mg 5 g
Category
Type Molecules
Specific against other
Purity 98.0
Citations [1]Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231.
Smiles O=C(O)CCOCCOCCOCCOCCN=[N+]=[N-]
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Shipping Condition Cool pack
Available
Manufacturer - Type
ADC Related
Manufacturer - Applications
COVID-19-immunoregulation
Manufacturer - Targets
ADC Linker; PROTAC Linkers
Shipping Temperature
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Molecular Weight
291.30
Product Description
Azido-PEG4-C2-acid a PEG-based PROTAC linker can be used in the synthesis of vRucaparib-TP4. Azido-PEG4-C2-acid is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG4-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Manufacturer - Research Area
Cancer; Inflammation/Immunology
Solubility
DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway
Antibody-drug Conjugate/ADC Related; PROTAC
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 g
Available: In stock
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